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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CADPS2
All Species:
36.06
Human Site:
Y586
Identified Species:
79.33
UniProt:
Q86UW7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UW7
NP_001009571.2
1296
147735
Y586
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
Y
Chimpanzee
Pan troglodytes
XP_001146490
1296
147661
Y586
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
Y
Rhesus Macaque
Macaca mulatta
XP_001084178
1297
147885
Y587
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
Y
Dog
Lupus familis
XP_532534
1204
137239
N539
M
D
E
F
I
S
A
N
P
C
K
L
D
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR5
1297
147822
Y590
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
Y
Rat
Rattus norvegicus
Q62717
1289
146248
Y618
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507532
1359
153617
Y644
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
Y
Chicken
Gallus gallus
XP_001233823
1325
150564
Y596
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
H
Frog
Xenopus laevis
Q6GLR7
1299
148702
Y587
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NHE5
1436
162680
D666
D
S
I
S
F
A
C
D
D
E
N
E
C
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23658
1396
159184
Y726
H
L
W
V
Q
A
L
Y
R
A
T
G
Q
A
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
88.4
N.A.
95.9
77
N.A.
85.3
77.6
77.1
N.A.
N.A.
53.7
N.A.
44.7
N.A.
Protein Similarity:
100
100
99.4
90.4
N.A.
98.1
86.7
N.A.
90.1
87.6
87.7
N.A.
N.A.
68.8
N.A.
63.3
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
93.3
N.A.
100
93.3
93.3
N.A.
N.A.
13.3
N.A.
80
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
100
N.A.
N.A.
13.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
91
10
0
0
82
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% C
% Asp:
10
10
0
0
0
0
0
10
10
0
0
0
10
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
28
% H
% Ile:
73
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
82
0
0
0
0
10
0
0
0
0
10
0
0
10
% L
% Met:
10
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
82
0
0
0
0
0
0
0
82
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% R
% Ser:
0
10
0
10
0
10
0
0
0
0
0
0
0
82
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% T
% Val:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
55
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _